Computer-aided synthetic biology

Prof. Dr. Johannes Kabisch

Microbial biotechnology offers novel solutions for some of the problems our society faces today, such as depletion of resources, pollution and lack of sustainability. Our central research theme is the creation of microbial cell factories helping us to tackle these challenges.

Automation & Rapid Prototyping

We research how to combine robotic and software development to allow to push developments in Synthetic Biology. Our robots can generate strains, optimize media and autonomously perform promoter characterizations.

Spore Display

The development of new and easy to use platforms for the immobilization of enzymes on the surface of bacterial spores of the Gram-positive bacteria Bacillus subtilis and Paenibacillus polymyxae is the scope of our spore display projects. To improve our hosts we reduces their genomes, rewire regulatory pathways and develop methods to rapidly improve processes using automation. We apply these technologies together with partners from industry and academia worldwide in applied projects.

Renewable Lipids

Using oleaginous yeasts like Yarrowia lipolytica we research strain and bioprocess designs to enable the renewable production of lipids and derived products such as hydrocarbons to be used as biofuels.

Funding is provided by